Treatment of Idiopathic Membranous Nephropathy
نویسندگان
چکیده
منابع مشابه
Treatment of idiopathic membranous nephropathy.
Exciting progress recently has been made in our understanding of idiopathic membranous nephropathy, as well as treatment of this disease. Here, we review important advances regarding the pathogenesis of membranous nephropathy. We will also review the current approach to treatment and its limitations and will highlight new therapies that are currently being explored for this disease including Ri...
متن کاملIdiopathic membranous nephropathy: diagnosis and treatment.
Idiopathic membranous nephropathy is still the most common glomerular disease associated with nephrotic syndrome. The greater the proteinuria, the greater the long-term risk for renal failure. In addition, patients who have membranous nephropathy with nephrotic syndrome have significant morbidity and mortality, in particular related to thromboembolic and cardiovascular complications. There is n...
متن کاملTreatment with rituximab in idiopathic membranous nephropathy
BACKGROUND Rituximab represents a valid therapeutic option to induce remission in patients with primary glomerulonephritis. Despite several studies proving its efficacy in improving outcomes in patients with membranous nephropathy (MN), its role in therapeutic protocols is not yet defined. METHODS We studied 38 patients with idiopathic MN treated with rituximab (in 13 patients as first-line t...
متن کاملChapter 7: Idiopathic membranous nephropathy
BACKGROUND The diagnosis of MN is made on kidney biopsy. Diagnostic features include capillary wall thickening, normal cellularity, IgG and C3 along capillary walls on immunofluorescence, and subepithelial deposits on electron microscopy. MN is often seen in association with an underlying disorder (secondary MN). Secondary MN is more common in children (75%) than adults (25%) (Table 12). The di...
متن کاملEffective treatment of four consecutive idiopathic membranous nephropathy patients.
lies in the way information on ACEI/ARB treatment was obtained. In the study of Opelz et al., a questionnaire was sent out, with a return rate of 107 out of 299 participating centres. Their publication does not provide information on how completely the data was collected within those 107 centres. By contrast, we used data bases from the general public Austrian Sickness Funds and direct entry fr...
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ژورنال
عنوان ژورنال: Journal of the American Society of Nephrology
سال: 2012
ISSN: 1046-6673,1533-3450
DOI: 10.1681/asn.2012010058